Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein

BACKGROUND: BRF2 is a transcription factor required for synthesis of a small group of non-coding RNAs by RNA polymerase III. Overexpression of BRF2 can transform human mammary epithelial cells. In both breast and lung cancers, the BRF2 gene is amplified and overexpressed and may serve as an oncogeni...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Koo, Jana, Cabarcas-Petroski, Stephanie, Petrie, John L., Diette, Nicole, White, Robert J., Schramm, Laura
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647806/
https://ncbi.nlm.nih.gov/pubmed/26573593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1914-5
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