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Targeting LKB1 in cancer – exposing and exploiting vulnerabilities
The LKB1 tumour suppressor is a serine/threonine kinase that functions as master regulator of cell growth, metabolism, survival and polarity. LKB1 is frequently mutated in human cancers and research spanning the last two decades have begun decoding the cellular pathways deregulated following LKB1 in...
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| Publicado no: | Br J Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647688/ https://ncbi.nlm.nih.gov/pubmed/26196184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.261 |
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