Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice

BACKGROUND: Growth arrest and DNA damage-inducible protein 34 (GADD34/Ppp1r15a) is a family of GADD proteins that are induced by DNA damage. GADD34 protein has been suggested to regulate inflammation or host defense systems. However, the in vivo function of GADD34 in inflammation is still unclear. L...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Tanaka, Yuriko, Ito, Sachiko, Oshino, Reina, Chen, Nana, Nishio, Naomi, Isobe, Ken-ichi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Molecular Diagnostics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647681/
https://ncbi.nlm.nih.gov/pubmed/26196182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.263
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