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GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy

Autophagy is a common physiological function in all eukaryotes. The process is induced by depletion of nutrients including amino acids. GADD34 is expressed following DNA damage, ER stresses and amino acid deprivation. Here, we investigated the effects of GADD34 on autophagy and cell activation in ma...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ito, Sachiko, Tanaka, Yuriko, Oshino, Reina, Aiba, Keiko, Thanasegaran, Suganya, Nishio, Naomi, Isobe, Ken-ichi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321179/
https://ncbi.nlm.nih.gov/pubmed/25659802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08327
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