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Expression of pEGFR and pAKT as response-predictive biomarkers for RAS wild-type patients to anti-EGFR monoclonal antibodies in metastatic colorectal cancers
BACKGROUND: RAS wild-type (RAS(w/t)) tumours have been associated with better outcomes in patients with metastatic colorectal cancer (mCRC) treated with anti-EGFR monoclonal antibodies (mAb). We investigated the expression of EGFR downstream proteins under their active phosphorylated forms as potent...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Br J Cancer |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647679/ https://ncbi.nlm.nih.gov/pubmed/26171935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.250 |
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