Combination of sorafenib and gadolinium chloride (GdCl3) attenuates dimethylnitrosamine(DMN)-induced liver fibrosis in rats

BACKGROUND/AIMS: Liver sinusoidal endothelial cells (SECs), hepatic stellate cells (HSCs) and Kupffer cells (KCs) are involved in the development of liver fibrosis and represent a potential therapeutic target. The therapeutic effects on liver fibrosis of sorafenib, a multiple tyrosine kinase inhibit...

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書誌詳細
出版年:BMC Gastroenterol
主要な著者: Liu, Cheng, Yang, Zongguo, Wang, Lei, Lu, Yunfei, Tang, Bozong, Miao, Hui, Xu, Qingnian, Chen, Xiaorong
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647665/
https://ncbi.nlm.nih.gov/pubmed/26572488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0380-5
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