Combination of sorafenib and gadolinium chloride (GdCl3) attenuates dimethylnitrosamine(DMN)-induced liver fibrosis in rats

BACKGROUND/AIMS: Liver sinusoidal endothelial cells (SECs), hepatic stellate cells (HSCs) and Kupffer cells (KCs) are involved in the development of liver fibrosis and represent a potential therapeutic target. The therapeutic effects on liver fibrosis of sorafenib, a multiple tyrosine kinase inhibit...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Liu, Cheng, Yang, Zongguo, Wang, Lei, Lu, Yunfei, Tang, Bozong, Miao, Hui, Xu, Qingnian, Chen, Xiaorong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647665/
https://ncbi.nlm.nih.gov/pubmed/26572488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0380-5
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