Targeted amplification for enhanced detection of biothreat agents by next-generation sequencing

BACKGROUND: Historically, identification of causal agents of disease has relied heavily on the ability to culture the organism in the laboratory and/or the use of pathogen-specific antibodies or sequence-based probes. However, these methods can be limiting: Even highly sensitive PCR-based assays mus...

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Bibliografiske detaljer
Udgivet i:BMC Res Notes
Main Authors: Gardner, Shea N., Frey, Kenneth G., Redden, Cassie L., Thissen, James B., Allen, Jonathan E., Allred, Adam F., Dyer, Matthew D., Mokashi, Vishwesh P., Slezak, Tom R.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647626/
https://ncbi.nlm.nih.gov/pubmed/26572552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-015-1530-0
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