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A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence
Polycomb-like proteins 1–3 (PCL1–3) are substoichiometric components of the Polycomb-repressive complex 2 (PRC2) that are essential for association of the complex with chromatin. However, it remains unclear why three proteins with such apparent functional redundancy exist in mammals. Here we charact...
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| Udgivet i: | Genes Dev |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647557/ https://ncbi.nlm.nih.gov/pubmed/26494712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.267930.115 |
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