Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study

BACKGROUND: MYCN amplification with subsequent MYCN protein overexpression is a powerful indicator of poor prognosis of neuroblastoma patients. Little is known regarding the prognostic significance of the homologous MYC protein expression in neuroblastoma. METHODS: Immunostaining for MYCN and MYC pr...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Wang, L L, Teshiba, R, Ikegaki, N, Tang, X X, Naranjo, A, London, W B, Hogarty, M D, Gastier-Foster, J M, Look, A T, Park, J R, Maris, J M, Cohn, S L, Seeger, R C, Asgharzadeh, S, Shimada, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647535/
https://ncbi.nlm.nih.gov/pubmed/26035700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.188
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