Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis

Although much progress has been made in identifying the mechanisms that trigger endothelial activation and inflammatory cell recruitment during atherosclerosis, less is known about the intrinsic pathways that counteract these events. Here we identified NOTCH1 as an antagonist of endothelial cell (EC...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Briot, Anaïs, Civelek, Mete, Seki, Atsuko, Hoi, Karen, Mack, Julia J., Lee, Stephen D., Kim, Jason, Hong, Cynthia, Yu, Jingjing, Fishbein, Gregory A., Vakili, Ladan, Fogelman, Alan M., Fishbein, Michael C., Lusis, Aldons J., Tontonoz, Peter, Navab, Mohamad, Berliner, Judith A., Iruela-Arispe, M. Luisa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2015
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647265/
https://ncbi.nlm.nih.gov/pubmed/26552708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150603
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