Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis

Although much progress has been made in identifying the mechanisms that trigger endothelial activation and inflammatory cell recruitment during atherosclerosis, less is known about the intrinsic pathways that counteract these events. Here we identified NOTCH1 as an antagonist of endothelial cell (EC...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Briot, Anaïs, Civelek, Mete, Seki, Atsuko, Hoi, Karen, Mack, Julia J., Lee, Stephen D., Kim, Jason, Hong, Cynthia, Yu, Jingjing, Fishbein, Gregory A., Vakili, Ladan, Fogelman, Alan M., Fishbein, Michael C., Lusis, Aldons J., Tontonoz, Peter, Navab, Mohamad, Berliner, Judith A., Iruela-Arispe, M. Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647265/
https://ncbi.nlm.nih.gov/pubmed/26552708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150603
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