Transcriptional repressor ZEB2 promotes terminal differentiation of CD8(+) effector and memory T cell populations during infection

ZEB2 is a multi-zinc-finger transcription factor known to play a significant role in early neurogenesis and in epithelial-mesenchymal transition–dependent tumor metastasis. Although the function of ZEB2 in T lymphocytes is unknown, activity of the closely related family member ZEB1 has been implicat...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Omilusik, Kyla D., Best, J. Adam, Yu, Bingfei, Goossens, Steven, Weidemann, Alexander, Nguyen, Jessica V., Seuntjens, Eve, Stryjewska, Agata, Zweier, Christiane, Roychoudhuri, Rahul, Gattinoni, Luca, Bird, Lynne M., Higashi, Yujiro, Kondoh, Hisato, Huylebroeck, Danny, Haigh, Jody, Goldrath, Ananda W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647262/
https://ncbi.nlm.nih.gov/pubmed/26503445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150194
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