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Focal-adhesion-independent integrin-αv regulation of FAK and c-Myc is necessary for 3D skin formation and tumor invasion

Integrins play crucial roles in epithelial adhesion, proliferation, wound healing and cancer. In the epidermis, the roles of many integrin subunits are incompletely defined and mechanistic details regarding their functions are lacking. We performed a multiplexed small hairpin (sh)RNA screen to defin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Sci
Egile Nagusiak: Duperret, Elizabeth K., Dahal, Ankit, Ridky, Todd W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647167/
https://ncbi.nlm.nih.gov/pubmed/26359297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175539
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