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Native proteins trap high-energy transit conformations

During protein folding and as part of some conformational changes that regulate protein function, the polypeptide chain must traverse high-energy barriers that separate the commonly adopted low-energy conformations. How distortions in peptide geometry allow these barrier-crossing transitions is a fu...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Brereton, Andrew E., Karplus, P. Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646835/
https://ncbi.nlm.nih.gov/pubmed/26601321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501188
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