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Native proteins trap high-energy transit conformations
During protein folding and as part of some conformational changes that regulate protein function, the polypeptide chain must traverse high-energy barriers that separate the commonly adopted low-energy conformations. How distortions in peptide geometry allow these barrier-crossing transitions is a fu...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646835/ https://ncbi.nlm.nih.gov/pubmed/26601321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501188 |
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