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Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures

We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA) subtypes to chemotherapeutics and molecular targeted agents. Primary cultures of mucin- and mixed-IHCCA were prepared from surgical specimens (N. 18 IHCCA patients) and evaluated for cell proliferation (MTS assay) and apoptos...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Fraveto, Alice, Cardinale, Vincenzo, Bragazzi, Maria Consiglia, Giuliante, Felice, De Rose, Agostino Maria, Grazi, Gian Luca, Napoletano, Chiara, Semeraro, Rossella, Lustri, Anna Maria, Costantini, Daniele, Nevi, Lorenzo, Di Matteo, Sabina, Renzi, Anastasia, Carpino, Guido, Gaudio, Eugenio, Alvaro, Domenico
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646673/
https://ncbi.nlm.nih.gov/pubmed/26571380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142124
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