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Decreased nicotinic receptor availability in smokers with slow rates of nicotine metabolism
The nicotine metabolite ratio (NMR), a stable measure of hepatic nicotine metabolism via the CYP2A6 pathway and total nicotine clearance, is a predictive biomarker of response to nicotine replacement therapy, with increased quit rates in slower metabolizers. Nicotine binds directly to nicotinic acet...
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| Pubblicato in: | J Nucl Med |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646418/ https://ncbi.nlm.nih.gov/pubmed/26272810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.155002 |
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