Interleukin 10 (IL-10)-mediated Immunosuppression: MARCH-I INDUCTION REGULATES ANTIGEN PRESENTATION BY MACROPHAGES BUT NOT DENDRITIC CELLS

Efficient immune responses require regulated antigen presentation to CD4 T cells. IL-10 inhibits the ability of dendritic cells (DCs) and macrophages to stimulate antigen-specific CD4 T cells; however, the mechanisms by which IL-10 suppresses antigen presentation remain poorly understood. We now rep...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mittal, Sharad K., Cho, Kyung-Jin, Ishido, Satoshi, Roche, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646393/
https://ncbi.nlm.nih.gov/pubmed/26408197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682708
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