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Francisella tularensis Elicits IL-10 via a PGE(2)-Inducible Factor, to Drive Macrophage MARCH1 Expression and Class II Down-Regulation
Francisella tularensis is a bacterial pathogen that uses host-derived PGE(2) to subvert the host's adaptive immune responses in multiple ways. Francisella-induced PGE(2) acts directly on CD4 T cells to blunt production of IFN-γ. Francisella-induced PGE(2) can also elicit production of a >10...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355121/ https://ncbi.nlm.nih.gov/pubmed/22615981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037330 |
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