Lateral Diffusion, Function, and Expression of the Slow Channel Congenital Myasthenia Syndrome αC418W Nicotinic Receptor Mutation with Changes in Lipid Raft Components

Lipid rafts, specialized membrane microdomains in the plasma membrane rich in cholesterol and sphingolipids, are hot spots for a number of important cellular processes. The novel nicotinic acetylcholine receptor (nAChR) mutation αC418W, the first lipid-exposed mutation identified in a patient that c...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Oyola-Cintrón, Jessica, Caballero-Rivera, Daniel, Ballester, Leomar, Baéz-Pagán, Carlos A., Martínez, Hernán L., Vélez-Arroyo, Karla P., Quesada, Orestes, Lasalde-Dominicci, José A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646332/
https://ncbi.nlm.nih.gov/pubmed/26354438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678573
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