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Evidence of Distinct Channel Conformations and Substrate Binding Affinities for the Mitochondrial Outer Membrane Protein Translocase Pore Tom40

Nearly all mitochondrial proteins are coded by the nuclear genome and must be transported into mitochondria by the translocase of the outer membrane complex. Tom40 is the central subunit of the translocase complex and forms a pore in the mitochondrial outer membrane. To date, the mechanism it utiliz...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Kuszak, Adam J., Jacobs, Daniel, Gurnev, Philip A., Shiota, Takuya, Louis, John M., Lithgow, Trevor, Bezrukov, Sergey M., Rostovtseva, Tatiana K., Buchanan, Susan K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646270/
https://ncbi.nlm.nih.gov/pubmed/26336107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642173
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