Evidence of Distinct Channel Conformations and Substrate Binding Affinities for the Mitochondrial Outer Membrane Protein Translocase Pore Tom40

Nearly all mitochondrial proteins are coded by the nuclear genome and must be transported into mitochondria by the translocase of the outer membrane complex. Tom40 is the central subunit of the translocase complex and forms a pore in the mitochondrial outer membrane. To date, the mechanism it utiliz...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kuszak, Adam J., Jacobs, Daniel, Gurnev, Philip A., Shiota, Takuya, Louis, John M., Lithgow, Trevor, Bezrukov, Sergey M., Rostovtseva, Tatiana K., Buchanan, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646270/
https://ncbi.nlm.nih.gov/pubmed/26336107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642173
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