Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import

The preprotein translocase of the outer mitochondrial membrane (TOM) functions as the main entry gate for the import of nuclear-encoded proteins into mitochondria. The major subunits of the TOM complex are the three receptors Tom20, Tom22, and Tom70 and the central channel-forming protein Tom40. Cyt...

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Hlavní autoři: Rao, Sanjana, Schmidt, Oliver, Harbauer, Angelika B., Schönfisch, Birgit, Guiard, Bernard, Pfanner, Nikolaus, Meisinger, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338429/
https://ncbi.nlm.nih.gov/pubmed/22419819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0933
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