Altered Lipid Synthesis by Lack of Yeast Pah1 Phosphatidate Phosphatase Reduces Chronological Life Span

In Saccharomyces cerevisiae, Pah1 phosphatidate phosphatase, which catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol, plays a crucial role in the synthesis of the storage lipid triacylglycerol. This evolutionarily conserved enzyme also plays a negative regulatory role in contr...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Park, Yeonhee, Han, Gil-Soo, Mileykovskaya, Eugenia, Garrett, Teresa A., Carman, George M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Lipids
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646187/
https://ncbi.nlm.nih.gov/pubmed/26338708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680314
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