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A conserved tryptophan within the WRDPLVDID domain of yeast Pah1 phosphatidate phosphatase is required for its in vivo function in lipid metabolism

PAH1-encoded phosphatidate phosphatase, which catalyzes the dephosphorylation of phosphatidate to produce diacylglycerol at the endoplasmic reticulum membrane, plays a major role in controlling the utilization of phosphatidate for the synthesis of triacylglycerol or membrane phospholipids. The conse...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Park, Yeonhee, Han, Gil-Soo, Carman, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712600/
https://ncbi.nlm.nih.gov/pubmed/29066621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.819375
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