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CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics

CLIP-associated proteins CLASPs are mammalian microtubule (MT) plus-end tracking proteins (+TIPs) that promote MT rescue in vivo. Their plus-end localization is dependent on other +TIPs, EB1 and CLIP-170, but in the leading edge of the cell, CLASPs display lattice-binding activity. MT association of...

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Bibliografiska uppgifter
I publikationen:J Mol Biol
Huvudupphovsmän: Maki, Takahisa, Grimaldi, Ashley D., Fuchigami, Sotaro, Kaverina, Irina, Hayashi, Ikuko
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646087/
https://ncbi.nlm.nih.gov/pubmed/26003921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.05.012
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