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An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue

Microtubules are heavily regulated dynamic polymers of αβ-tubulin that are required for proper chromosome segregation and organization of the cytoplasm. Polymerases in the XMAP215 family use arrayed TOG domains to promote faster microtubule elongation. Regulatory factors in the cytoplasmic linker as...

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Pubblicato in:Mol Biol Cell
Autori principali: Majumdar, Shreoshi, Kim, Tae, Chen, Zhe, Munyoki, Sarah, Tso, Shih-Chia, Brautigam, Chad A., Rice, Luke M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994897/
https://ncbi.nlm.nih.gov/pubmed/29851564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-12-0748
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