PAX-FOXO1 Fusion Status Drives Unfavorable Outcome for Children With Rhabdomyosarcoma: A Children’s Oncology Group Report

BACKGROUND: Rhabdomyosarcoma (RMS) is divided into two major histological subtypes: alveolar (ARMS) and embryonal (ERMS), with most ARMS expressing one of two oncogenic genes fusing PAX3 or PAX7 with FOXO1 (P3F and P7F, respectively). The Children’s Oncology Group (COG) carried out a multi-instituti...

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發表在:Pediatr Blood Cancer
Main Authors: Skapek, Stephen X., Anderson, James, Barr, Frederic G., Bridge, Julia A., Gastier-Foster, Julie M., Parham, David M., Rudzinski, Erin R., Triche, Timothy, Hawkins, Douglas S.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646073/
https://ncbi.nlm.nih.gov/pubmed/23526739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24532
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