PAX-FOXO1 Fusion Status Drives Unfavorable Outcome for Children With Rhabdomyosarcoma: A Children’s Oncology Group Report

BACKGROUND: Rhabdomyosarcoma (RMS) is divided into two major histological subtypes: alveolar (ARMS) and embryonal (ERMS), with most ARMS expressing one of two oncogenic genes fusing PAX3 or PAX7 with FOXO1 (P3F and P7F, respectively). The Children’s Oncology Group (COG) carried out a multi-instituti...

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Detaylı Bibliyografya
Yayımlandı:Pediatr Blood Cancer
Asıl Yazarlar: Skapek, Stephen X., Anderson, James, Barr, Frederic G., Bridge, Julia A., Gastier-Foster, Julie M., Parham, David M., Rudzinski, Erin R., Triche, Timothy, Hawkins, Douglas S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646073/
https://ncbi.nlm.nih.gov/pubmed/23526739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24532
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