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Chemical Synthesis of a Glycopeptide Derived from Skp1 for Probing Protein Specific Glycosylation

Skp1 is a cytoplasmic and nuclear protein, best known as an adaptor of the SCF family of E3-ubiquitin ligases that label proteins for their degradation. Skp1 in Dictyostelium is posttranslationally modified on a specific hydroxyproline (Hyp) residue by a pentasaccharide, which consists of a Fucα1,2-...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Chinoy, Zoeisha S., Schafer, Christopher M., West, Christopher M., Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646072/
https://ncbi.nlm.nih.gov/pubmed/26179871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201501598
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