The Silent Sway of Splicing by Synonymous Substitutions

Alternative splicing diversifies mRNA transcripts in human cells. This sequence-driven process can be influenced greatly by mutations, even those that do not change the protein coding potential of the transcript. Synonymous mutations have been shown to alter gene expression through modulation of spl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mueller, William F., Larsen, Liza S. Z., Garibaldi, Angela, Hatfield, G. Wesley, Hertel, Klemens J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646019/
https://ncbi.nlm.nih.gov/pubmed/26424794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684035
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