The Silent Sway of Splicing by Synonymous Substitutions

Alternative splicing diversifies mRNA transcripts in human cells. This sequence-driven process can be influenced greatly by mutations, even those that do not change the protein coding potential of the transcript. Synonymous mutations have been shown to alter gene expression through modulation of spl...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Mueller, William F., Larsen, Liza S. Z., Garibaldi, Angela, Hatfield, G. Wesley, Hertel, Klemens J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646019/
https://ncbi.nlm.nih.gov/pubmed/26424794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684035
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