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G Run-mediated Recognition of Proteolipid Protein and DM20 5′ Splice Sites by U1 Small Nuclear RNA Is Regulated by Context and Proximity to the Splice Site

Highly conserved G runs, G1M2 and ISE, regulate the proteolipid protein (PLP)/DM20 ratio. We have investigated recruitment of U1 small nuclear ribonuclear protein (snRNP) by G1M2 and ISE and examined the effect of splice site strength, distance, and context on G run function. G1M2 is necessary for i...

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Bibliografski detalji
Glavni autori: Wang, Erming, Mueller, William F., Hertel, Klemens J., Cambi, Franca
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039333/
https://ncbi.nlm.nih.gov/pubmed/21127064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199927
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