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G Run-mediated Recognition of Proteolipid Protein and DM20 5′ Splice Sites by U1 Small Nuclear RNA Is Regulated by Context and Proximity to the Splice Site
Highly conserved G runs, G1M2 and ISE, regulate the proteolipid protein (PLP)/DM20 ratio. We have investigated recruitment of U1 small nuclear ribonuclear protein (snRNP) by G1M2 and ISE and examined the effect of splice site strength, distance, and context on G run function. G1M2 is necessary for i...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039333/ https://ncbi.nlm.nih.gov/pubmed/21127064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199927 |
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