Subcellular Distribution of NAD(+) between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells

The mitochondrial NAD pool is particularly important for the maintenance of vital cellular functions. Although at least in some fungi and plants, mitochondrial NAD is imported from the cytosol by carrier proteins, in mammals, the mechanism of how this organellar pool is generated has remained obscur...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: VanLinden, Magali R., Dölle, Christian, Pettersen, Ina K. N., Kulikova, Veronika A., Niere, Marc, Agrimi, Gennaro, Dyrstad, Sissel E., Palmieri, Ferdinando, Nikiforov, Andrey A., Tronstad, Karl Johan, Ziegler, Mathias
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646015/
https://ncbi.nlm.nih.gov/pubmed/26432643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654129
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