Subcellular Distribution of NAD(+) between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells

The mitochondrial NAD pool is particularly important for the maintenance of vital cellular functions. Although at least in some fungi and plants, mitochondrial NAD is imported from the cytosol by carrier proteins, in mammals, the mechanism of how this organellar pool is generated has remained obscur...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: VanLinden, Magali R., Dölle, Christian, Pettersen, Ina K. N., Kulikova, Veronika A., Niere, Marc, Agrimi, Gennaro, Dyrstad, Sissel E., Palmieri, Ferdinando, Nikiforov, Andrey A., Tronstad, Karl Johan, Ziegler, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646015/
https://ncbi.nlm.nih.gov/pubmed/26432643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654129
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