Subcellular Distribution of NAD(+) between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells

The mitochondrial NAD pool is particularly important for the maintenance of vital cellular functions. Although at least in some fungi and plants, mitochondrial NAD is imported from the cytosol by carrier proteins, in mammals, the mechanism of how this organellar pool is generated has remained obscur...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: VanLinden, Magali R., Dölle, Christian, Pettersen, Ina K. N., Kulikova, Veronika A., Niere, Marc, Agrimi, Gennaro, Dyrstad, Sissel E., Palmieri, Ferdinando, Nikiforov, Andrey A., Tronstad, Karl Johan, Ziegler, Mathias
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Metabolism
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646015/
https://ncbi.nlm.nih.gov/pubmed/26432643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654129
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