Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification

Queuosine (Q) is a hypermodified RNA base that replaces guanine in the wobble positions of 5′-GUN-3′ tRNA molecules. Q is exclusively made by bacteria, and the corresponding queuine base is a micronutrient salvaged by eukaryotic species. The final step in Q biosynthesis is the reduction of the epoxi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Payne, Karl A. P., Fisher, Karl, Sjuts, Hanno, Dunstan, Mark S., Bellina, Bruno, Johannissen, Linus, Barran, Perdita, Hay, Sam, Rigby, Stephen E. J., Leys, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646009/
https://ncbi.nlm.nih.gov/pubmed/26378237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.685693
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky