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Regulation of PACT-Mediated Protein Kinase Activation by the OV20.0 Protein of Orf Virus

Double-stranded RNA (dsRNA)-activated protein kinase (PKR), a major component of the cellular antiviral system, is activated by the binding of either dsRNA or the cellular PKR activator, the PACT protein. The suppression of PKR activation is one of the main strategies that viruses employ to circumve...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Tseng, Yeu-Yang, Liao, Guan-Ru, Sen, Ganes C., Lin, Fong-Yuan, Hsu, Wei-Li
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645672/
https://ncbi.nlm.nih.gov/pubmed/26355092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01739-15
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