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Adenosine Deaminase Acting on RNA 1 Associates with Orf Virus OV20.0 and Enhances Viral Replication

Orf virus (ORFV) infects sheep and goats and is also an important zoonotic pathogen. The viral protein OV20.0 has been shown to suppress innate immunity by targeting the double-stranded RNA (dsRNA)-activated protein kinase (PKR) by multiple mechanisms. These mechanisms include a direct interaction w...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Liao, Guan-Ru, Tseng, Yeu-Yang, Tseng, Ching-Yu, Lin, Fong-Yuan, Yamada, Yumiko, Liu, Hao-Ping, Kuan, Chih-Ying, Hsu, Wei-Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430553/
https://ncbi.nlm.nih.gov/pubmed/30651363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01912-18
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