Phenotypic Correlates of HIV-1 Macrophage Tropism

HIV-1 is typically CCR5 using (R5) and T cell tropic (T-tropic), targeting memory CD4(+) T cells throughout acute and chronic infections. However, viruses can expand into alternative cells types. Macrophage-tropic (M-tropic) HIV-1 variants have evolved to infect macrophages, which have only low leve...

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Vydáno v:J Virol
Hlavní autoři: Arrildt, Kathryn T., LaBranche, Celia C., Joseph, Sarah B., Dukhovlinova, Elena N., Graham, William D., Ping, Li-Hua, Schnell, Gretja, Sturdevant, Christa B., Kincer, Laura P., Mallewa, Macpherson, Heyderman, Robert S., Van Rie, Annelies, Cohen, Myron S., Spudich, Serena, Price, Richard W., Montefiori, David C., Swanstrom, Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645658/
https://ncbi.nlm.nih.gov/pubmed/26339058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00946-15
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