Central Nervous System Compartmentalization of HIV-1 Subtype C Variants Early and Late in Infection in Young Children

HIV-1 subtype B replication in the CNS can occur in CD4+ T cells or macrophages/microglia in adults. However, little is known about CNS infection in children or the ability of subtype C HIV-1 to evolve macrophage-tropic variants. In this study, we examined HIV-1 variants in ART-naïve children aged t...

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Detalhes bibliográficos
Main Authors: Sturdevant, Christa Buckheit, Dow, Anna, Jabara, Cassandra B., Joseph, Sarah B., Schnell, Gretja, Takamune, Nobutoki, Mallewa, Macpherson, Heyderman, Robert S., Van Rie, Annelies, Swanstrom, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531524/
https://ncbi.nlm.nih.gov/pubmed/23300446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003094
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