Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses

Animal viruses frequently cause zoonotic disease in humans. As these viruses are highly diverse, evaluating the threat that they pose remains a major challenge, and efficient approaches are needed to rapidly predict virus-host compatibility. Here, we develop a combined computational and experimental...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kerr, Scott A., Jackson, Eleisha L., Lungu, Oana I., Meyer, Austin G., Demogines, Ann, Ellington, Andrew D., Georgiou, George, Wilke, Claus O., Sawyer, Sara L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645654/
https://ncbi.nlm.nih.gov/pubmed/26355089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01408-15
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