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Analyzing machupo virus-receptor binding by molecular dynamics simulations

In many biological applications, we would like to be able to computationally predict mutational effects on affinity in protein–protein interactions. However, many commonly used methods to predict these effects perform poorly in important test cases. In particular, the effects of multiple mutations,...

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Podrobná bibliografie
Hlavní autoři: Meyer, Austin G., Sawyer, Sara L., Ellington, Andrew D., Wilke, Claus O.
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940602/
https://ncbi.nlm.nih.gov/pubmed/24624315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.266
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