Changes in Structural-Mechanical Properties and Degradability of Collagen during Aging-associated Modifications

During aging, changes occur in the collagen network that contribute to various pathological phenotypes in the skeletal, vascular, and pulmonary systems. The aim of this study was to investigate the consequences of age-related modifications on the mechanical stability and in vitro proteolytic degrada...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Panwar, Preety, Lamour, Guillaume, Mackenzie, Neil C. W., Yang, Heejae, Ko, Frank, Li, Hongbin, Brömme, Dieter
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645626/
https://ncbi.nlm.nih.gov/pubmed/26224630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.644310
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