STAT1 Signaling within Macrophages Is Required for Antifungal Activity against Cryptococcus neoformans

Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an opportunistic fungal pathogen that primarily affects AIDS patients and patients undergoing immunosuppressive therapy. In immunocompromised individuals, C. neoformans can lead to life-threatening meningoencephalitis....

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Vydáno v:Infect Immun
Hlavní autoři: Leopold Wager, Chrissy M., Hole, Camaron R., Wozniak, Karen L., Olszewski, Michal A., Mueller, Mathias, Wormley, Floyd L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645398/
https://ncbi.nlm.nih.gov/pubmed/26351277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00935-15
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