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Early Vertebrate Evolution of the Host Restriction Factor Tetherin

Tetherin is an interferon-inducible restriction factor targeting a broad range of enveloped viruses. Its antiviral activity depends on an unusual topology comprising an N-terminal transmembrane domain (TMD) followed by an extracellular coiled-coil region and a C-terminal glycosylphosphatidylinositol...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Heusinger, Elena, Kluge, Silvia F., Kirchhoff, Frank, Sauter, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645306/
https://ncbi.nlm.nih.gov/pubmed/26401043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02149-15
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