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Molecular Evolution of the Primate Antiviral Restriction Factor Tetherin
BACKGROUND: Tetherin is a recently identified antiviral restriction factor that restricts HIV-1 particle release in the absence of the HIV-1 viral protein U (Vpu). It is reminiscent of APOBEC3G and TRIM5a that also antagonize HIV. APOBEC3G and TRIM5a have been demonstrated to evolve under pervasive...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912774/ https://ncbi.nlm.nih.gov/pubmed/20689591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011904 |
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