Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis

[Image: see text] Oral squamous cell carcinoma (OSCC) is the most common cancer affecting the oral cavity, and US clinics will register about 30,000 new patients in 2015. Current treatment modalities include chemotherapy, surgery, and radiotherapy, which often result in astonishing disfigurement. Ca...

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Pubblicato in:ACS Med Chem Lett
Autori principali: Sidhu, Alpa, Miller, Justin R., Tripathi, Ashootosh, Garshott, Danielle M., Brownell, Amy L., Chiego, Daniel J., Arevang, Carl, Zeng, Qinghua, Jackson, Leah C., Bechler, Shelby A., Callaghan, Michael U., Yoo, George H., Sethi, Seema, Lin, Ho-Sheng, Callaghan, Joseph H., Tamayo-Castillo, Giselle, Sherman, David H., Kaufman, Randal J., Fribley, Andrew M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645248/
https://ncbi.nlm.nih.gov/pubmed/26617965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00133
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