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FOXO1 inhibits osteoclastogenesis partially by antagnozing MYC

FOXO transcription factors especially FOXO1 have profound roles in bone development and remodeling. The regulation of cells of the osteoblast lineage by FOXOs is suggested to be stage-specific or context dependent. Intriguingly, recent studies on the role played by FOXOs in osteoclastogenesis reache...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Tan, Peng, Guan, Hanfeng, Xie, Linka, Mi, Baoguo, Fang, Zhong, Li, Jing, Li, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645183/
https://ncbi.nlm.nih.gov/pubmed/26568463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16835
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