טוען...
Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays
Rho-associated kinases (ROCKs) have been regarded as promising drug targets for the treatment of cardiovascular diseases, nervous system diseases and cancers. In this study, a novel integrated virtual screening protocol by combining molecular docking and pharmacophore mapping based on multiple ROCK1...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645114/ https://ncbi.nlm.nih.gov/pubmed/26568382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16749 |
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