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The second virial coefficient as a predictor of protein aggregation propensity: A self-interaction chromatography study
The second osmotic virial coefficients (b(2)) of four proteins – lysozyme, recombinant human lactoferrin, concanavalin A and catalase were measured by self-interaction chromatography (SIC) in solutions of varying salt type, concentration and pH. Protein aggregate sizes based on the initial hydrodyna...
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| Publicado no: | Eur J Pharm Biopharm |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4644993/ https://ncbi.nlm.nih.gov/pubmed/26259782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2015.07.025 |
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