Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon

The colon tumor microenvironment (TME) is becoming increasingly recognized as a complex but central player in the development of many cancers. Previously, we identified an oncogenic role for the mRNA-binding protein IMP1 (IGF2BP1) in the epithelium during colon tumorigenesis. In the current study, w...

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Pubblicato in:Mol Cancer Res
Autori principali: Hamilton, Kathryn E., Chatterji, Priya, Lundsmith, Emma T., Andres, Sarah F., Giroux, Veronique, Hicks, Philip D., Noubissi, Felicite K., Spiegelman, Vladimir S., Rustgi, Anil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644674/
https://ncbi.nlm.nih.gov/pubmed/26194191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0224
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